| Gene Information | |
|---|---|
| Gene Name | CHMP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 222 |
| Protein Names | Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000115561 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y3E7 |
| Gene Card | CHMP3 |
| Uniprot ID | Q9Y3E7 |
| Pfam | PF03357 |
| In ASD | no |
| Allosteric Prediction | no (-0.744109621) |
| Ortholog in Animals | Alpaca_ CHMP3 ( ortholog_one2one ) Dog_ CHMP3 ( ortholog_one2one ) GuineaPig_ CHMP3 ( ortholog_one2one ) Mouse_ Chmp3 ( ortholog_one2one ) Pig_ CHMP3 ( ortholog_one2one ) Rat_ Chmp3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHMP2B, CHMP2A, CHMP1B, CHMP1A |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:15632132}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2GD5 (X-ray 2.80A ) 2XZE (X-ray 1.75A ) 3FRT (X-ray 4.00A ) 3FRV (X-ray 3.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol. Membrane; Lipid-anchor. Endosome. Late endosome membrane {ECO:0000305}. Note=Localizes to the midbody of dividing cells. |
| Mouse PG classification | NA |
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