| Gene Information | |
|---|---|
| Gene Name | LEMD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 911 |
| Protein Names | Inner nuclear membrane protein Man1 (LEM domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000174106 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y2U8 |
| Gene Card | LEMD3 |
| Uniprot ID | Q9Y2U8 |
| Pfam | PF03020; PF09402 |
| In ASD | no |
| Allosteric Prediction | no (-1.000088935) |
| Ortholog in Animals | Alpaca_ LEMD3 ( ortholog_one2one ) Dog_ LEMD3 ( ortholog_one2one ) GuineaPig_ LEMD3 ( ortholog_one2one ) Macaque_ LEMD3 ( ortholog_one2one ) Mouse_ Lemd3 ( ortholog_one2one ) Pig_ LEMD3 ( ortholog_one2one ) Rat_ Lemd3 ( ortholog_one2one ) Rabbit_ LEMD3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LEMD2, ANKLE1 |
| Tissue | NA |
| Tissue Specificity | Heart, brain, placenta, lung, liver and skeletal muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CH0 (NMR - ) 5ZOJ (X-ray 2.79A ) 5ZOK (X-ray 2.85A ) |
| DBSNP | rs7487311 |
| Subcellular location [CC] | Nucleus inner membrane {ECO:0000269|PubMed:15647271}; Multi-pass membrane protein {ECO:0000269|PubMed:15647271}. |
| Mouse PG classification | LPG |
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