Gene Information
Gene NameOBFC2B
OrganismHomo sapiens (Human)
Gene Length211
Protein NamesSOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9BQ15
Gene CardNABP2
Uniprot IDQ9BQ15
PfamPF01336
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4OWT  (X-ray  2.00A  4OWW  (X-ray  2.30A  4OWX  (X-ray  2.30A  5D8E  (X-ray  3.00A  5D8F  (X-ray  2.35A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:18449195, ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}. Note=Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment.
Mouse PG classificationNA
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