| Gene Information | |
|---|---|
| Gene Name | MCH2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 293 |
| Protein Names | Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P55212 |
| Gene Card | CASP6 |
| Uniprot ID | P55212 |
| Pfam | NA |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2WDP (X-ray 1.95A ) 3K7E (X-ray 3.00A ) 3NKF (X-ray 2.90A ) 3NR2 (X-ray 2.90A ) 3OD5 (X-ray 1.60A ) 3P45 (X-ray 2.53A ) 3P4U (X-ray 1.90A ) 3QNW (X-ray 2.65A ) 3S70 (X-ray 1.62A ) 3S8E (X-ray 2.88A ) 3V6L (X-ray 2.20A ) 3V6M (X-ray 2.69A ) 4EJF (X-ray 2.65A ) 4FXO (X-ray 2.85A ) 4HVA (X-ray 2.07A ) 4IYR (X-ray 2.70A ) 4N5D (X-ray 2.06A ) 4N6G (X-ray 2.14A ) 4N7J (X-ray 1.67A ) 4N7M (X-ray 2.12A ) 4NBK (X-ray 1.94A ) 4NBL (X-ray 1.76A ) 4NBN (X-ray 1.75A ) 6DEU (X-ray 2.80A ) 6DEV (X-ray 2.35A ) |
| DBSNP | rs11574697 rs5030674 rs5030593 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:27911442}. Nucleus {ECO:0000269|PubMed:27911442}. |
| Mouse PG classification | NA |
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