| Gene Information | |
|---|---|
| Gene Name | MCEF |
| Organism | Homo sapiens (Human) |
| Gene Length | 1163 |
| Protein Names | AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UHB7 |
| Gene Card | AFF4 |
| Uniprot ID | Q9UHB7 |
| Pfam | PF18876; PF18875 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Strongly expressed in heart, placenta, skeletal muscle, pancreas and to a lower extent in brain. {ECO:0000269|PubMed:10588740, ECO:0000269|PubMed:12065898}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003263(Rat);0.052632(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4IMY (X-ray 2.94A ) 4OGR (X-ray 3.00A ) 4OR5 (X-ray 2.90A ) 5JW9 (X-ray 2.00A ) 5L1Z (X-ray 5.90A ) 6CYT (X-ray 3.50A ) 6K7P (X-ray 2.40A ) 6KN5 (X-ray 2.20A ) 6R80 (X-ray 2.20A ) |
| DBSNP | rs34527550 rs786205233 rs786205679 rs786205680 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12065898}. Note=Associates to transcriptionally active chromatin but not at snRNA genes. {ECO:0000250}. |
| Mouse PG classification | NA |
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