Gene Information
Gene NameGUSB
OrganismHomo sapiens (Human)
Gene Length651
Protein NamesBeta-glucuronidase (EC 3.2.1.31) (Beta-G1)
Target Namebeta-glucuronidase
Target TypeSuccessful target
Gene Age886 ( ENSG00000169919 )
Evolutionary StageCellular_organisms
AlphaFoldDBP08236
Gene CardGUSB
Uniprot IDP08236
PfamPF00703; PF02836; PF02837
In ASDno
Allosteric Predictionyes (0.955561981)
Ortholog in AnimalsAlpaca_ GUSB ( ortholog_one2one )
Alpaca_ GUSB ( ortholog_one2many )
Dog_ GUSB ( ortholog_one2one )
GuineaPig_ GUSB ( ortholog_one2one )
Mouse_ Gusb ( ortholog_one2one )
Pig_ GUSB ( ortholog_one2one )
Rat_ Gusb ( ortholog_one2one )
Rabbit_ GUSB ( ortholog_one2one )
OhnologsNA
ParalogsMANBA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1BHG  (X-ray  2.53A  3HN3  (X-ray  1.70A 
DBSNP rs747792546  rs779499448  rs1424546265  rs1417426295  rs121918177  rs149606212  rs121918181  rs121918174  rs886044680  rs121918182  rs191153460  rs121918175  rs398123234  rs771629102  rs747572640  rs11559283  rs121918173  rs764018631  rs779091113  rs751025746  rs774393243  rs121918178  rs121918183  rs1250112198  rs121918176  rs121918172  rs777613366  rs121918184  rs9530 
Subcellular location [CC]Lysosome.
Mouse PG classificationNA
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