| Gene Information | |
|---|---|
| Gene Name | MCC |
| Organism | Homo sapiens (Human) |
| Gene Length | 829 |
| Protein Names | Colorectal mutant cancer protein (Protein MCC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000171444 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P23508 |
| Gene Card | MCC |
| Uniprot ID | P23508 |
| Pfam | PF10506 |
| In ASD | no |
| Allosteric Prediction | no (-0.281848341) |
| Ortholog in Animals | Alpaca_ MCC ( ortholog_one2one ) Dog_ MCC ( ortholog_one2one ) GuineaPig_ MCC ( ortholog_one2one ) Macaque_ MCC ( ortholog_one2one ) Mouse_ Mcc ( ortholog_one2one ) Pig_ MCC ( ortholog_one2one ) Rat_ Mcc ( ortholog_one2one ) Rabbit_ MCC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | USHBP1 |
| Tissue | NA |
| Tissue Specificity | Expressed in a variety of tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6MTU (X-ray 2.14A ) 6MTV (X-ray 2.60A ) |
| DBSNP | rs185322500 rs6594681 rs35269015 rs760495893 rs121917732 rs121917731 rs17313892 |
| Subcellular location [CC] | Cell membrane. Cell projection, lamellipodium. Nucleus {ECO:0000269|PubMed:24824780}. Cytoplasm {ECO:0000269|PubMed:24824780}. Note=Colocalizes with actin at the leading edge of polarized cells. |
| Mouse PG classification | NA |
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