| Gene Information | |
|---|---|
| Gene Name | MC3R |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Melanocortin receptor 3 (MC3-R) |
| Target Name | melanocortin receptor 3 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000124089 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P41968 |
| Gene Card | MC3R |
| Uniprot ID | P41968 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.199205807) |
| Ortholog in Animals | Alpaca_ MC3R ( ortholog_one2one ) Dog_ MC3R ( ortholog_one2one ) GuineaPig_ MC3R ( ortholog_one2one ) Macaque_ MC3R ( ortholog_one2one ) Mouse_ Mc3r ( ortholog_one2one ) Pig_ MC3R ( ortholog_one2one ) Rat_ Mc3r ( ortholog_one2one ) Rabbit_ MC3R ( ortholog_one2one ) |
| Ohnologs | LPAR2, GPR6, MC4R, MC5R, GPR3 |
| Paralogs | S1PR1, S1PR5, S1PR2, S1PR3, S1PR4, LPAR1, LPAR2, LPAR3, GPR3, GPR119, GPR6, GPR12, CNR1, CNR2, MC4R, MC5R, MC2R, MC1R |
| Tissue | NA |
| Tissue Specificity | Brain, placental, and gut tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3827103 rs74315393 rs121913556 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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