| Gene Information | |
|---|---|
| Gene Name | PRSS15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 959 |
| Protein Names | Lon protease homolog, mitochondrial (EC 3.4.21.53) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P36776 |
| Gene Card | LONP1 |
| Uniprot ID | P36776 |
| Pfam | PF00004; PF05362; PF02190 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Duodenum, heart, lung and liver, but not thymus. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2X36 (X-ray 2.00A ) 6WYS (X-ray 2.23A ) 6WZV (X-ray 2.51A ) 6X1M (X-ray 3.51A ) 6X27 (X-ray 2.12A ) 7KRZ (EM 3.20A ) 7KSL (EM 3.40A ) 7KSM (EM 3.20A ) 7NFY (EM 3.90A ) 7NG4 (EM 4.40A ) 7NG5 (EM 3.80A ) 7NGC (EM 7.50A ) 7NGF (EM 5.60A ) 7NGL (EM 3.80A ) 7NGP (EM 15.00A ) 7NGQ (EM 12.00A ) 7OXO (EM 3.90A ) 7P09 (EM 2.70A ) 7P0B (EM 4.00A ) 7P0M (EM 2.75A ) |
| DBSNP | rs34413649 rs11085147 rs879255248 rs770036526 rs777009012 rs879255247 rs549574673 rs147588238 rs879255249 rs562553348 rs35804229 rs1062373 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000255|HAMAP-Rule:MF_03120, ECO:0000269|PubMed:7961901}. |
| Mouse PG classification | NA |
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