| Gene Information | |
|---|---|
| Gene Name | SCYL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 808 |
| Protein Names | N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase) |
| Target Name | n-terminal kinase-like protein |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000142186 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96KG9 |
| Gene Card | SCYL1 |
| Uniprot ID | Q96KG9 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.553462224) |
| Ortholog in Animals | Alpaca_ SCYL1 ( ortholog_one2one ) Dog_ SCYL1 ( ortholog_one2one ) GuineaPig_ SCYL1 ( ortholog_one2one ) Mouse_ Scyl1 ( ortholog_one2one ) Pig_ SCYL1 ( ortholog_one2one ) Rat_ Scyl1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCYL3, SCYL2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12036289}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002240(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs55977709 rs56076708 rs56077405 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18556652}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:18556652}. Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:18556652}. Note=Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner.; [Isoform 1]: Cytoplasm. Note=Cytoplasmic throughout the cell cycle.; [Isoform 2]: Cytoplasm. Note=Cytoplasmic throughout the cell cycle.; [Isoform 3]: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic during interphase and centrosomal during mitosis, it localizes to the centrosomes in a microtubule-independent manner.; [Isoform 6]: Nucleus {ECO:0000269|PubMed:15504359}. |
| Mouse PG classification | NA |
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