| Gene Information | |
|---|---|
| Gene Name | AGMAT |
| Organism | Homo sapiens (Human) |
| Gene Length | 352 |
| Protein Names | Agmatinase, mitochondrial (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000116771 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9BSE5 |
| Gene Card | AGMAT |
| Uniprot ID | Q9BSE5 |
| Pfam | PF00491 |
| In ASD | no |
| Allosteric Prediction | no (-0.252934761) |
| Ortholog in Animals | Alpaca_ AGMAT ( ortholog_one2one ) Dog_ AGMAT ( ortholog_one2one ) GuineaPig_ AGMAT ( ortholog_one2one ) Macaque_ AGMAT ( ortholog_one2one ) Mouse_ Agmat ( ortholog_one2one ) Pig_ AGMAT ( ortholog_one2one ) Rat_ Agmat ( ortholog_one2one ) Rabbit_ AGMAT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARG2, ARG1 |
| Tissue | kidney, artery, colon, parotid.gland, cortex.of.kidney, liver |
| Tissue Specificity | Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain, testis, skin and the gastrointestinal tract. Within brain, expression is higher in the cerebral cortex with lower levels in the medulla and spinal cord. {ECO:0000269|PubMed:11804860, ECO:0000269|PubMed:11914032}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6429757 rs11580170 |
| Subcellular location [CC] | Mitochondrion. |
| Mouse PG classification | NA |
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