| Gene Information | |
|---|---|
| Gene Name | MBD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 291 |
| Protein Names | Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000071655 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95983 |
| Gene Card | MBD3 |
| Uniprot ID | O95983 |
| Pfam | PF01429; PF14048; PF16564 |
| In ASD | no |
| Allosteric Prediction | no (-0.271665523) |
| Ortholog in Animals | Alpaca_ MBD3 ( ortholog_one2one ) Dog_ MBD3 ( ortholog_one2one ) GuineaPig_ MBD3 ( ortholog_one2one ) Macaque_ MBD3 ( ortholog_one2one ) Mouse_ Mbd3 ( ortholog_one2one ) Pig_ MBD3 ( ortholog_one2one ) Rat_ Mbd3 ( ortholog_one2one ) |
| Ohnologs | MBD3L1, MBD2 |
| Paralogs | MBD3L1, MBD3L2B, MBD3L5, MBD3L2, MBD3L3, MBD3L4, MBD1, MBD2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.114753(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MB7 (NMR - ) 6CC8 (X-ray 1.95A ) 6CCG (X-ray 1.90A ) 6CEU (X-ray 2.00A ) 6CEV (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Chromosome. Note=Nuclear, in discrete foci. Detected on chromatin, at promoter regions of active genes. |
| Mouse PG classification | NA |
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