| Gene Information | |
|---|---|
| Gene Name | MBC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1104 |
| Protein Names | Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BSJ8 |
| Gene Card | ESYT1 |
| Uniprot ID | Q9BSJ8 |
| Pfam | PF00168; PF17047 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:17360437}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35075600 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:29469807}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:29469807}; Peripheral membrane protein {ECO:0000269|PubMed:29469807}. Note=Localizes primarily to the endoplasmic reticulum (PubMed:29469807). Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels (PubMed:29469807, PubMed:22250200). {ECO:0000269|PubMed:22250200, ECO:0000269|PubMed:29469807}. |
| Mouse PG classification | NA |
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