| Gene Information | |
|---|---|
| Gene Name | CCT6A |
| Organism | Homo sapiens (Human) |
| Gene Length | 531 |
| Protein Names | T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (HTR3) (Tcp20) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000146731 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P40227 |
| Gene Card | CCT6A |
| Uniprot ID | P40227 |
| Pfam | PF00118 |
| In ASD | no |
| Allosteric Prediction | yes (0.444009907) |
| Ortholog in Animals | Alpaca_ CCT6A ( ortholog_one2one ) Alpaca_ CCT6A ( ortholog_one2many ) Dog_ CCT6A ( ortholog_one2one ) GuineaPig_ CCT6A ( ortholog_one2one ) Macaque_ CCT6A ( ortholog_one2one ) Mouse_ Cct6a ( ortholog_one2one ) Pig_ CCT6A ( ortholog_one2one ) Rat_ Cct6a ( ortholog_one2many ) Rabbit_ CCT6A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TCP1, BBS12, CCT2, CCT4, CCT6B, CCT7, CCT5, HSPD1, CCT8L2, CCT8, CCT3, PIKFYVE, MKKS |
| Tissue | substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001731(Rat);0.196267(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6NR8 (EM 7.80A ) 6NR9 (EM 8.50A ) 6NRA (EM 7.70A ) 6NRB (EM 8.70A ) 6NRC (EM 8.30A ) 6NRD (EM 8.20A ) 6QB8 (EM 3.97A ) 7LUM (EM 4.50A ) 7LUP (EM 6.20A ) 7NVL (EM 2.50A ) 7NVM (EM 3.10A ) 7NVN (EM 3.00A ) 7NVO (EM 3.50A ) |
| DBSNP | rs33922584 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:8034610}. |
| Mouse PG classification | NA |
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