| Gene Information | |
|---|---|
| Gene Name | MAZ |
| Organism | Homo sapiens (Human) |
| Gene Length | 477 |
| Protein Names | Myc-associated zinc finger protein (MAZI) (Pur-1) (Purine-binding transcription factor) (Serum amyloid A-activating factor-1) (SAF-1) (Transcription factor Zif87) (ZF87) (Zinc finger protein 801) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000103495 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P56270 |
| Gene Card | MAZ |
| Uniprot ID | P56270 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.830755555) |
| Ortholog in Animals | Alpaca_ MAZ ( ortholog_one2one ) Dog_ MAZ ( ortholog_one2one ) GuineaPig_ MAZ ( ortholog_one2one ) Macaque_ MAZ ( ortholog_one2one ) Mouse_ Maz ( ortholog_one2one ) Pig_ MAZ ( ortholog_one2one ) Rat_ Maz ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZNF575, ZNF276, HIC1, ZNF653, ZNF362, ZNF410, PATZ1, MTF1, PRDM1, HIC2, ZNF76, ZFP91, PRDM6, ZNF296, ZBTB1, SNAI3, SNAI2, ZBTB20, ZNF281, ZBTB18, ZNF143, ZBTB16, SNAI1, ZNF148, ZBTB32, ZBTB45, ZBTB7C, ZBTB42, ZNF451, ZNF692, PRDM14, VEZF1, SCRT2, SCRT1, ZNF384, PRDM10 |
| Tissue | NA |
| Tissue Specificity | Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level). {ECO:0000269|PubMed:10727212}.; [Isoform 1]: Expressed in the heart, brain, placenta, lung, liver, skeletal muscle and weakly expressed in the kidney (PubMed:1502157). Expressed in the joint synovium (PubMed:19583771). {ECO:0000269|PubMed:1502157, ECO:0000269|PubMed:19583771}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:10727212}. Note=In brains of Alzheimer disease patients, present in a plaque-like structures. |
| Mouse PG classification | NA |
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