Gene Information
Gene NameMAX
OrganismHomo sapiens (Human)
Gene Length160
Protein NamesProtein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000125952 )
Evolutionary StageOpisthokonta
AlphaFoldDBP61244
Gene CardMAX
Uniprot IDP61244
PfamPF00010
In ASDno
Allosteric Predictionno (-0.175245355)
Ortholog in AnimalsAlpaca_ MAX ( ortholog_one2one )
Dog_ MAX ( ortholog_one2one )
GuineaPig_ MAX ( ortholog_one2one )
Macaque_ MAX ( ortholog_one2one )
Mouse_ Max ( ortholog_one2one )
Pig_ MAX ( ortholog_one2one )
Rat_ Max ( ortholog_one2one )
Rabbit_ MAX ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHigh levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.019048(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1AN2  (X-ray  2.90A  1HLO  (X-ray  2.80A  1NKP  (X-ray  1.80A  1NLW  (X-ray  2.00A  1R05  (NMR  5EYO  (X-ray  2.39A  6G6J  (X-ray  2.25A  6G6K  (X-ray  1.35A  6G6L  (X-ray  2.20A 
DBSNP rs201743423  rs2063106124  rs772912674  rs760147253 
Subcellular location [CC]Nucleus. Cell projection, dendrite {ECO:0000250}.
Mouse PG classificationLPG
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