| Gene Information | |
|---|---|
| Gene Name | GPC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 556 |
| Protein Names | Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000076716 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75487 |
| Gene Card | GPC4 |
| Uniprot ID | O75487 |
| Pfam | PF01153 |
| In ASD | no |
| Allosteric Prediction | no (-0.280467518) |
| Ortholog in Animals | Alpaca_ GPC4 ( ortholog_one2one ) Dog_ GPC4 ( ortholog_one2one ) GuineaPig_ GPC4 ( ortholog_one2one ) Macaque_ GPC4 ( ortholog_one2one ) Mouse_ Gpc4 ( ortholog_one2one ) Pig_ GPC4 ( ortholog_one2one ) Rat_ Gpc4 ( ortholog_one2one ) Rabbit_ GPC4 ( ortholog_one2one ) |
| Ohnologs | GPC1, GPC5, GPC6, GPC2 |
| Paralogs | GPC6, GPC1, GPC2, GPC3, GPC5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1129980 rs1556022962 rs1048369 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.; [Secreted glypican-4]: Secreted, extracellular space {ECO:0000250}. |
| Mouse PG classification | NA |
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