| Gene Information | |
|---|---|
| Gene Name | MARK |
| Organism | Homo sapiens (Human) |
| Gene Length | 795 |
| Protein Names | Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9P0L2 |
| Gene Card | MARK1 |
| Uniprot ID | Q9P0L2 |
| Pfam | PF02149; PF00069; PF00627 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney. {ECO:0000269|PubMed:9108484}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HAK (X-ray 2.60A ) 3OSE (X-ray 1.70A ) 6C9D (X-ray 2.50A ) |
| DBSNP | rs56212551 rs55691439 rs12123778 rs55688276 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:21145462}; Peripheral membrane protein {ECO:0000269|PubMed:21145462}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:23666762}. Cell projection, dendrite {ECO:0000269|PubMed:23666762}. Note=Appears to localize to an intracellular network. {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |