| Gene Information | |
|---|---|
| Gene Name | MARE |
| Organism | Homo sapiens (Human) |
| Gene Length | 569 |
| Protein Names | GATOR complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q12980 |
| Gene Card | NPRL3 |
| Uniprot ID | Q12980 |
| Pfam | PF03666 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in the frontal lobe cortex as well as in the temporal, parietal, and occipital lobes (PubMed:27173016, PubMed:26505888). {ECO:0000269|PubMed:26505888, ECO:0000269|PubMed:27173016}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6CES (EM 4.00A ) 6CET (EM 4.40A ) 7T3A (EM 4.00A ) 7T3B (EM 3.90A ) 7T3C (EM 4.00A ) |
| DBSNP | rs367729589 rs200041907 |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:28199306}. Note=Localization to lysosomes is amino acid-independent. {ECO:0000269|PubMed:28199306}. |
| Mouse PG classification | NA |
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