| Gene Information | |
|---|---|
| Gene Name | SLC25A18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 315 |
| Protein Names | Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000182902 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H1K4 |
| Gene Card | SLC25A18 |
| Uniprot ID | Q9H1K4 |
| Pfam | PF00153 |
| In ASD | no |
| Allosteric Prediction | no (-0.459236377) |
| Ortholog in Animals | Alpaca_ SLC25A18 ( ortholog_one2one ) Dog_ SLC25A18 ( ortholog_one2one ) GuineaPig_ SLC25A18 ( ortholog_one2one ) Macaque_ SLC25A18 ( ortholog_one2one ) Mouse_ Slc25a18 ( ortholog_one2one ) Rat_ Slc25a18 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC25A23, SLC25A35, SLC25A38, SLC25A12, SLC25A11, SLC25A22, SLC25A29, UCP3, SLC25A21, SLC25A48, SLC25A42, SLC25A3, SLC25A28, UCP2, UCP1, SLC25A34, SLC25A15, SLC25A32, SLC25A53, SLC25A4, SLC25A40, SLC25A10, SLC25A24, SLC25A44, SLC25A31, SLC25A5, SLC25A39, SLC25A36, SLC25A14, SLC25A27, SLC25A1, SLC25A41, SLC25A43, SLC25A47, SLC25A20, SLC25A37, SLC25A13, SLC25A33, SLC25A25, SLC25A26, SLC25A6, SLC25A45, SLC25A2, SLC25A51, SLC25A52, SLC25A30, SLC25A19, SLC25A16, SLC25A17 |
| Tissue | adipose.tissue, brain, liver, cerebral.cortex |
| Tissue Specificity | Expressed in brain, to a lesser extent in testis, and poorly in all the other tissues. {ECO:0000269|PubMed:11897791}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q505J6}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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