| Gene Information | |
|---|---|
| Gene Name | SLC29A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 475 |
| Protein Names | Equilibrative nucleoside transporter 3 (hENT3) (Solute carrier family 29 member 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198246 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BZD2 |
| Gene Card | SLC29A3 |
| Uniprot ID | Q9BZD2 |
| Pfam | PF01733 |
| In ASD | no |
| Allosteric Prediction | no (-1.000235629) |
| Ortholog in Animals | Alpaca_ SLC29A3 ( ortholog_one2one ) Dog_ SLC29A3 ( ortholog_one2one ) GuineaPig_ SLC29A3 ( ortholog_one2one ) Macaque_ SLC29A3 ( ortholog_one2one ) Mouse_ Slc29a3 ( ortholog_one2one ) Pig_ SLC29A3 ( ortholog_one2one ) Rat_ Slc29a3 ( ortholog_one2one ) Rabbit_ SLC29A3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC29A2, SLC29A1, SLC29A4 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in both adult and fetal tissues. Highest levels in placenta, uterus, ovary, spleen, lymph node and bone marrow. Lowest levels in brain and heart. {ECO:0000269|PubMed:15701636}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2277257 rs267607057 rs1430557607 rs780668 rs143557881 rs1023257012 rs2252996 rs79737301 rs2487068 rs387907066 rs387907067 rs144517514 rs121912583 rs121912584 rs267607058 rs999940 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. Late endosome membrane. Lysosome membrane. Note=Observed in a punctate intracellular pattern showing partial colocalization with late endosomes/lysosomes. Not detected at the cell surface. |
| Mouse PG classification | NA |
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