| Gene Information | |
|---|---|
| Gene Name | MECOM |
| Organism | Homo sapiens (Human) |
| Gene Length | 1230 |
| Protein Names | Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000085276 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q03112 |
| Gene Card | MECOM |
| Uniprot ID | Q03112 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | yes (0.234312196) |
| Ortholog in Animals | Alpaca_ MECOM ( ortholog_one2one ) Dog_ MECOM ( ortholog_one2one ) GuineaPig_ MECOM ( ortholog_one2one ) Macaque_ MECOM ( ortholog_one2one ) Mouse_ Mecom ( ortholog_one2one ) Pig_ MECOM ( ortholog_one2one ) Rat_ Mecom ( ortholog_one2one ) Rabbit_ MECOM ( ortholog_one2one ) |
| Ohnologs | PRDM16 |
| Paralogs | PRDM16 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6BW3 (X-ray 2.20A ) |
| DBSNP | rs7622799 rs34896995 rs864309724 rs864309723 rs864309722 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11568182, ECO:0000269|PubMed:15897867, ECO:0000269|PubMed:9665135}. Nucleus speckle {ECO:0000269|PubMed:11568182}. Cytoplasm {ECO:0000269|PubMed:22939622}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |