| Gene Information | |
|---|---|
| Gene Name | DMRT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 373 |
| Protein Names | Doublesex- and mab-3-related transcription factor 1 (DM domain expressed in testis protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000137090 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9Y5R6 |
| Gene Card | DMRT1 |
| Uniprot ID | Q9Y5R6 |
| Pfam | PF00751; PF12374 |
| In ASD | no |
| Allosteric Prediction | no (-1.120957554) |
| Ortholog in Animals | Alpaca_ DMRT1 ( ortholog_one2one ) Dog_ DMRT1 ( ortholog_one2one ) GuineaPig_ DMRT1 ( ortholog_one2one ) Mouse_ Dmrt1 ( ortholog_one2one ) Pig_ DMRT1 ( ortholog_one2one ) Rat_ Dmrt1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DMRTB1, DMRTA1, DMRT3, DMRT2, DMRTC2, DMRTA2, DMRTC1, DMRTC1B |
| Tissue | testis |
| Tissue Specificity | Testis-specific. Expressed in prostate cancer (at protein level). {ECO:0000269|PubMed:10857744, ECO:0000269|PubMed:23436708}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4YJ0 (X-ray 3.81A ) |
| DBSNP | rs3739583 rs902482318 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |