| Gene Information | |
|---|---|
| Gene Name | TAL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Class A basic helix-loop-helix protein 17) (bHLHa17) (Stem cell protein) (T-cell leukemia/lymphoma protein 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000162367 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P17542 |
| Gene Card | TAL1 |
| Uniprot ID | P17542 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.679327757) |
| Ortholog in Animals | Alpaca_ TAL1 ( ortholog_one2one ) Dog_ TAL1 ( ortholog_one2one ) GuineaPig_ TAL1 ( ortholog_one2one ) Macaque_ TAL1 ( ortholog_one2one ) Mouse_ Tal1 ( ortholog_one2one ) Pig_ TAL1 ( ortholog_one2one ) Rat_ Tal1 ( ortholog_one2one ) Rabbit_ TAL1 ( ortholog_one2one ) |
| Ohnologs | LYL1 |
| Paralogs | LYL1, NHLH1, TAL2, NHLH2 |
| Tissue | bone.marrow |
| Tissue Specificity | Leukemic stem cell. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YPA (X-ray 2.80A ) 2YPB (X-ray 2.87A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |