Gene Information
Gene NameGTF2F1
OrganismHomo sapiens (Human)
Gene Length517
Protein NamesGeneral transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000125651 )
Evolutionary StageEukaryota
AlphaFoldDBP35269
Gene CardGTF2F1
Uniprot IDP35269
PfamPF05793
In ASDno
Allosteric Predictionno (-0.736009472)
Ortholog in AnimalsAlpaca_ GTF2F1 ( ortholog_one2one )
Dog_ GTF2F1 ( ortholog_one2one )
GuineaPig_ GTF2F1 ( ortholog_one2one )
Mouse_ Gtf2f1 ( ortholog_one2one )
Pig_ GTF2F1 ( ortholog_one2one )
Rat_ Gtf2f1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.598799(Rat);0.246967(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1F3U  (X-ray  1.70A  1I27  (X-ray  1.02A  1J2X  (X-ray  2.00A  1NHA  (NMR  1ONV  (NMR  2K7L  (NMR  5IY6  (EM  7.20A  5IY7  (EM  8.60A  5IY8  (EM  7.90A  5IY9  (EM  6.30A  5IYA  (EM  5.40A  5IYB  (EM  3.90A  5IYC  (EM  3.90A  5IYD  (EM  3.90A  6O9L  (EM  7.20A  7EDX  (EM  4.50A  7EG7  (EM  6.20A  7EG8  (EM  7.40A  7EG9  (EM  3.70A  7EGA  (EM  4.10A  7EGB  (EM  3.30A  7EGC  (EM  3.90A  7ENA  (EM  4.07A  7ENC  (EM  4.13A  7LBM  (EM  4.80A  7NVR  (EM  4.50A  7NVS  (EM  2.80A  7NVT  (EM  2.90A  7NVU  (EM  2.50A  7NVY  (EM  7.30A  7NVZ  (EM  7.20A  7NW0  (EM  6.60A 
DBSNP rs34826931 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
click here to return to the previous page