| Gene Information | |
|---|---|
| Gene Name | MAPKAPK1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 740 |
| Protein Names | Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P51812 |
| Gene Card | RPS6KA3 |
| Uniprot ID | P51812 |
| Pfam | PF00069; PF00433 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues, highest levels in skeletal muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4D9T (X-ray 2.40A ) 4D9U (X-ray 2.40A ) 4JG6 (X-ray 2.60A ) 4JG7 (X-ray 3.00A ) 4JG8 (X-ray 3.10A ) 4NUS (X-ray 2.39A ) 4NW5 (X-ray 1.94A ) 4NW6 (X-ray 1.74A ) 5D9K (X-ray 2.55A ) 5D9L (X-ray 2.15A ) 7OPO (X-ray 2.75A ) |
| DBSNP | rs56218010 rs122454124 rs122454126 rs122454127 rs387906703 rs398122813 rs122454130 rs879027948 rs122454125 rs122454131 rs122454129 rs148050184 rs1271090915 rs35026425 rs28935171 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17213202}. Cytoplasm {ECO:0000269|PubMed:17213202}. |
| Mouse PG classification | NA |
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