| Gene Information | |
|---|---|
| Gene Name | PARVG |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | Gamma-parvin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000138964 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9HBI0 |
| Gene Card | PARVG |
| Uniprot ID | Q9HBI0 |
| Pfam | PF00307 |
| In ASD | no |
| Allosteric Prediction | no (-1.169253897) |
| Ortholog in Animals | Alpaca_ PARVG ( ortholog_one2one ) Dog_ PARVG ( ortholog_one2one ) GuineaPig_ PARVG ( ortholog_one2one ) Macaque_ PARVG ( ortholog_one2one ) Mouse_ Parvg ( ortholog_one2one ) Pig_ PARVG ( ortholog_one2one ) Rat_ Parvg ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PARVA, PARVB |
| Tissue | spleen, whole.blood |
| Tissue Specificity | Expressed predominantly in lymphoid organs, including spleen, thymus, lymph node, bone marrow and peripheral blood leukocytes and moderately in the digestive tract, including stomach, duodenum, jejunum, ileum, ileocecum and appendix, as well as in lung and liver. Also expressed in tumors, but at a lower level than in the corresponding normal tissues. {ECO:0000269|PubMed:11722847}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell junction, focal adhesion. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Constituent of focal adhesions. {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |