| Gene Information | |
|---|---|
| Gene Name | SIX3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 332 |
| Protein Names | Homeobox protein SIX3 (Sine oculis homeobox homolog 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000138083 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95343 |
| Gene Card | SIX3 |
| Uniprot ID | O95343 |
| Pfam | PF00046; PF16878 |
| In ASD | no |
| Allosteric Prediction | no (-1.003165184) |
| Ortholog in Animals | Alpaca_ SIX3 ( ortholog_one2one ) Dog_ SIX3 ( ortholog_one2one ) GuineaPig_ SIX3 ( ortholog_one2one ) Macaque_ SIX3 ( ortholog_one2one ) Mouse_ Six3 ( ortholog_one2one ) Pig_ SIX3 ( ortholog_one2one ) Rat_ Six3 ( ortholog_one2one ) |
| Ohnologs | SIX6 |
| Paralogs | SIX2, ANHX, SIX6, SIX1, SIX4, SIX5 |
| Tissue | caudate.nucleus, diencephalon, pituitary.gland, putamen, thalamus, brain, nucleus.accumbens |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs199823175 rs121917881 rs137853021 rs387906868 rs121917878 rs989286015 rs121917880 rs121917879 rs780942050 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q62233, ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Mouse PG classification | HPG |
| click here to return to the previous page | |