| Gene Information | |
|---|---|
| Gene Name | KIAA1060 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1091 |
| Protein Names | Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q08462 |
| Gene Card | ADCY2 |
| Uniprot ID | Q08462 |
| Pfam | PF16214; PF06327; PF00211 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Expressed in brain, especially in caudate nucleus, cerebellum and hippocampus. {ECO:0000269|PubMed:11549699, ECO:0000269|PubMed:8476432}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.003490(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13166360 rs34043481 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:15385642}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:11549699, ECO:0000269|PubMed:21228062}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:11549699}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |