| Gene Information | |
|---|---|
| Gene Name | KLK15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 256 |
| Protein Names | Kallikrein-15 (EC 3.4.21.-) (ACO protease) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000174562 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9H2R5 |
| Gene Card | KLK15 |
| Uniprot ID | Q9H2R5 |
| Pfam | PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.650621128) |
| Ortholog in Animals | Alpaca_ KLK15 ( ortholog_one2one ) Dog_ KLK4 ( ortholog_one2one ) GuineaPig_ KLK15 ( ortholog_one2one ) Macaque_ KLK15 ( ortholog_one2one ) Mouse_ Klk15 ( ortholog_one2one ) Pig_ KLK15 ( ortholog_one2one ) Rat_ Klk15 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | OVCH1, PLAT, PRSS48, PLGLB1, PLGLB2, PLG, TMPRSS12, GZMM, PRSS37, PRSS27, PRSS33, PRSS57, PRSS50, KLK9 |
| Tissue | NA |
| Tissue Specificity | Highest expression in the thyroid gland. Also expressed in the prostate, salivary, and adrenal glands and in the colon testis and kidney. {ECO:0000269|PubMed:11010966}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3212805 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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