| Gene Information | |
|---|---|
| Gene Name | GPR50 |
| Organism | Homo sapiens (Human) |
| Gene Length | 617 |
| Protein Names | Melatonin-related receptor (G protein-coupled receptor 50) (H9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000102195 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13585 |
| Gene Card | GPR50 |
| Uniprot ID | Q13585 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-0.046469054) |
| Ortholog in Animals | Alpaca_ GPR50 ( ortholog_one2one ) Dog_ GPR50 ( ortholog_one2one ) Macaque_ GPR50 ( ortholog_one2one ) Mouse_ Gpr50 ( ortholog_one2one ) Pig_ GPR50 ( ortholog_one2one ) Rat_ Gpr50 ( ortholog_one2one ) Rabbit_ GPR50 ( ortholog_one2one ) |
| Ohnologs | MTNR1B, MTNR1A |
| Paralogs | TACR2, OR9A2, NPY1R, MTNR1B, OR11H6, OR11H7, OR11H4, OR9A1P, OR9G1, NPY2R, MTNR1A, GPR75, OR11G2, MCHR2, MCHR1, GPR19, OR11A1, TACR1, TACR3, OR11H2, OR11H12, OR11H1, GPR83, PROKR2, PROKR1, GPR88, PRLHR, OR51F1, OR10X1, NPY5R, OR9A4, NPY4R2, NPY4R |
| Tissue | pituitary.gland |
| Tissue Specificity | Hypothalamus and pituitary. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs561077 rs13440581 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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