| Gene Information | |
|---|---|
| Gene Name | MNAR |
| Organism | Homo sapiens (Human) |
| Gene Length | 1130 |
| Protein Names | Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8IZL8 |
| Gene Card | PELP1 |
| Uniprot ID | Q8IZL8 |
| Pfam | PF08166; PF08167 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11481323}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9436 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:21326211}. Nucleus, nucleoplasm {ECO:0000269|PubMed:21326211}. Nucleus {ECO:0000269|PubMed:11481323}. Cytoplasm {ECO:0000269|PubMed:11481323}. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasm (By similarity). Also found associated with the plasma membrane. Mainly in cytoplasm in a subset of breast tumors. Localization is widely deregulated in endometrial cancers with predominantly cytoplasm localization in high-grade endometrial tumors (PubMed:16140940). {ECO:0000250|UniProtKB:Q9DBD5, ECO:0000269|PubMed:16140940}. |
| Mouse PG classification | NA |
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