Gene Information
Gene NameNMT1
OrganismHomo sapiens (Human)
Gene Length496
Protein NamesGlycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (HsNMT1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1) (Protein-lysine myristoyltransferase NMT1) (EC 2.3.1.-)
Target Nameglycylpeptide n-tetradecanoyltransferase 1
Target TypeNA
Gene Age>4290 ( ENSG00000136448 )
Evolutionary StageEukaryota
AlphaFoldDBP30419
Gene CardNMT1
Uniprot IDP30419
PfamPF01233; PF02799
In ASDno
Allosteric Predictionyes (0.507698303)
Ortholog in AnimalsAlpaca_ NMT1 ( ortholog_one2one )
Dog_ NMT1 ( ortholog_one2one )
GuineaPig_ NMT1 ( ortholog_one2one )
Macaque_ NMT1 ( ortholog_one2one )
Mouse_ Nmt1 ( ortholog_one2one )
Pig_ NMT1 ( ortholog_one2one )
Rat_ Nmt1 ( ortholog_one2one )
Rabbit_ NMT1 ( ortholog_one2one )
OhnologsNMT2
ParalogsNMT2
TissueNA
Tissue SpecificityHeart, gut, kidney, liver and placenta. {ECO:0000269|PubMed:1570339}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1RXT  (X-ray  3.00A  )  3IU1  (X-ray  1.42A  )  3IU2  (X-ray  1.73A  )  3IWE  (X-ray  1.79A  )  3JTK  (X-ray  1.61A  )  4C2Y  (X-ray  1.64A  )  4C2Z  (X-ray  2.08A  )  5MU6  (X-ray  1.88A  )  5NPQ  (X-ray  2.37A  )  5O6H  (X-ray  1.29A  )  5O6J  (X-ray  1.45A  )  5O9S  (X-ray  2.70A  )  5O9T  (X-ray  2.15A  )  5O9U  (X-ray  1.85A  )  5O9V  (X-ray  2.20A  )  5UUT  (X-ray  2.25A  )  6EHJ  (X-ray  2.10A  )  6F56  (X-ray  1.94A  )  6FZ2  (X-ray  2.05A  )  6FZ3  (X-ray  2.00A  )  6FZ5  (X-ray  1.89A  )  6PAV  (X-ray  2.52A  )  6QRM  (X-ray  2.30A  )  6SJZ  (X-ray  2.00A  )  6SK2  (X-ray  1.90A  )  6SK3  (X-ray  2.70A  )  6SK8  (X-ray  1.87A  )  6SKJ  (X-ray  2.80A  )  7RK3  (X-ray  2.05A  ) 
DBSNP rs3087878 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:9353336, ECO:0000269|PubMed:9506952}. Cytoplasm, cytosol {ECO:0000269|PubMed:9353336}. Membrane {ECO:0000269|PubMed:9506952};
Peripheral membrane protein {ECO:0000269|PubMed:9506952}. Note=Copurifies with ribosomes. {ECO:0000269|PubMed:9353336}.
Mouse PG classificationNA
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