| Gene Information | |
|---|---|
| Gene Name | MAOB |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) |
| Target Name | monoamine oxidase type b |
| Target Type | Successful target |
| Gene Age | 1714 ( ENSG00000069535 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P27338 |
| Gene Card | MAOB |
| Uniprot ID | P27338 |
| Pfam | PF01593 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000195527) |
| Ortholog in Animals | Alpaca_ MAOB ( ortholog_one2one ) Dog_ MAOB ( ortholog_one2one ) GuineaPig_ MAOB ( ortholog_one2one ) Macaque_ MAOB ( ortholog_one2one ) Mouse_ Maob ( ortholog_one2one ) Pig_ MAOB ( ortholog_one2one ) Rat_ Maob ( ortholog_one2one ) Rabbit_ MAOB ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KDM1A, MAOA, SMOX, PPOX, KDM1B, PAOX, IL4I1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.088150(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1GOS (X-ray 3.00A ) 1OJ9 (X-ray 2.30A ) 1OJA (X-ray 1.70A ) 1OJC (X-ray 2.40A ) 1OJD (X-ray 3.10A ) 1S2Q (X-ray 2.07A ) 1S2Y (X-ray 2.12A ) 1S3B (X-ray 1.65A ) 1S3E (X-ray 1.60A ) 2BK3 (X-ray 1.80A ) 2BK4 (X-ray 1.90A ) 2BK5 (X-ray 1.83A ) 2BYB (X-ray 2.20A ) 2C64 (X-ray 2.20A ) 2C65 (X-ray 1.70A ) 2C66 (X-ray 2.50A ) 2C67 (X-ray 1.70A ) 2C70 (X-ray 2.06A ) 2C72 (X-ray 2.00A ) 2C73 (X-ray 2.20A ) 2C75 (X-ray 1.70A ) 2C76 (X-ray 1.70A ) 2V5Z (X-ray 1.60A ) 2V60 (X-ray 2.00A ) 2V61 (X-ray 1.70A ) 2VRL (X-ray 2.40A ) 2VRM (X-ray 2.30A ) 2VZ2 (X-ray 2.30A ) 2XCG (X-ray 1.90A ) 2XFN (X-ray 1.60A ) 2XFO (X-ray 2.10A ) 2XFP (X-ray 1.66A ) 2XFQ (X-ray 2.20A ) 2XFU (X-ray 2.20A ) 3PO7 (X-ray 1.80A ) 3ZYX (X-ray 2.20A ) 4A79 (X-ray 1.89A ) 4A7A (X-ray 1.70A ) 4CRT (X-ray 1.80A ) 5MRL (X-ray 2.42A ) 6FVZ (X-ray 1.80A ) 6FW0 (X-ray 1.60A ) 6FWC (X-ray 1.70A ) 6RKB (X-ray 2.30A ) 6RKP (X-ray 1.70A ) 6RLE (X-ray 2.30A ) 6YT2 (X-ray 1.80A ) 7B0V (X-ray 2.30A ) 7B0Z (X-ray 2.10A ) 7P4F (X-ray 2.30A ) 7P4H (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. |
| Mouse PG classification | NA |
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