| Gene Information | |
|---|---|
| Gene Name | TBRG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 411 |
| Protein Names | Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000154144 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q3YBR2 |
| Gene Card | TBRG1 |
| Uniprot ID | Q3YBR2 |
| Pfam | PF05965; PF05964 |
| In ASD | no |
| Allosteric Prediction | no (-1.337295516) |
| Ortholog in Animals | Alpaca_ TBRG1 ( ortholog_one2one ) Dog_ TBRG1 ( ortholog_one2one ) GuineaPig_ TBRG1 ( ortholog_one2one ) Macaque_ TBRG1 ( ortholog_one2one ) Mouse_ Tbrg1 ( ortholog_one2one ) Pig_ TBRG1 ( ortholog_one2one ) Rat_ AABR07045058.1 ( ortholog_one2many ) Rat_ Tbrg1 ( ortholog_one2many ) Rabbit_ TBRG1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma. {ECO:0000269|PubMed:17110379}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2WZO (X-ray 1.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17110379}. |
| Mouse PG classification | NA |
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