| Gene Information | |
|---|---|
| Gene Name | GIMAP7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 300 |
| Protein Names | GTPase IMAP family member 7 (Immunity-associated nucleotide 7 protein) (IAN-7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 12 ( ENSG00000179144 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NHV1 |
| Gene Card | GIMAP7 |
| Uniprot ID | Q8NHV1 |
| Pfam | PF04548 |
| In ASD | no |
| Allosteric Prediction | no (-1.215904555) |
| Ortholog in Animals | Alpaca_ GIMAP7 ( ortholog_one2many ) Dog_ GIMAP7 ( ortholog_one2one ) Macaque_ GIMAP7 ( ortholog_one2one ) Mouse_ Gimap7 ( ortholog_one2one ) Rat_ Gimap7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GIMAP6, GIMAP5, GIMAP4, GIMD1, GIMAP1, GIMAP2, GIMAP8 |
| Tissue | NA |
| Tissue Specificity | Most abundantly expressed in spleen, lymph nodes, and fetal kidney, but also present in the heart and the small intestine. Lower expression levels are found in lung, kidney, liver, and thyroid, salivary, and mammary glands. Also detected in the thymus (PubMed:15474311). Detected in T-cells (PubMed:23454188). {ECO:0000269|PubMed:15474311, ECO:0000269|PubMed:23454188}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ZJC (X-ray 3.15A ) |
| DBSNP | rs3735080 |
| Subcellular location [CC] | Lipid droplet {ECO:0000269|PubMed:23454188}. Cytoplasm {ECO:0000269|PubMed:23454188}. Endoplasmic reticulum {ECO:0000269|PubMed:15474311}. Golgi apparatus {ECO:0000269|PubMed:15474311}. Note=Colocalizes with GIMAP2 on the surface of cytoplasmic lipid droplets. |
| Mouse PG classification | NA |
| click here to return to the previous page | |