| Gene Information | |
|---|---|
| Gene Name | MAN2A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1150 |
| Protein Names | Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000196547 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49641 |
| Gene Card | MAN2A2 |
| Uniprot ID | P49641 |
| Pfam | PF09261; PF07748; PF01074 |
| In ASD | no |
| Allosteric Prediction | no (-0.430646485) |
| Ortholog in Animals | Alpaca_ MAN2A2 ( ortholog_one2one ) Dog_ MAN2A2 ( ortholog_one2one ) GuineaPig_ MAN2A2 ( ortholog_one2one ) Macaque_ MAN2A2 ( ortholog_one2one ) Mouse_ Man2a2 ( ortholog_one2one ) Pig_ MAN2A2 ( ortholog_one2one ) Rat_ Man2a2 ( ortholog_one2one ) Rabbit_ MAN2A2 ( ortholog_one2one ) |
| Ohnologs | MAN2A1 |
| Paralogs | MAN2A1, MAN2B2, MAN2B1, MAN2C1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2106673 rs1266494 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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