Gene Information
Gene NameMAN2A1
OrganismHomo sapiens (Human)
Gene Length1144
Protein NamesAlpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)
Target Namegolgi alpha-mannosidase ii
Target TypeDiscontinued target
Gene Age950 ( ENSG00000112893 )
Evolutionary StageEukaryota
AlphaFoldDBQ16706
Gene CardMAN2A1
Uniprot IDQ16706
PfamPF09261; PF07748; PF01074
In ASDno
Allosteric Predictionno (-0.642805103)
Ortholog in AnimalsAlpaca_ MAN2A1 ( ortholog_one2one )
Dog_ MAN2A1 ( ortholog_one2one )
GuineaPig_ MAN2A1 ( ortholog_one2one )
Macaque_ MAN2A1 ( ortholog_one2one )
Mouse_ Man2a1 ( ortholog_one2one )
Pig_ MAN2A1 ( ortholog_one2one )
Rat_ Man2a1 ( ortholog_one2one )
Rabbit_ MAN2A1 ( ortholog_one2one )
OhnologsMAN2A2
ParalogsMAN2A2, MAN2B2, MAN2B1, MAN2C1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Golgi apparatus membrane {ECO:0000250|UniProtKB:P28494};
Single-pass type II membrane protein {ECO:0000250|UniProtKB:P28494}.
Mouse PG classificationNA
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