Gene Information
Gene NameMAN1C1
OrganismHomo sapiens (Human)
Gene Length630
Protein NamesMannosyl-oligosaccharide 1,2-alpha-mannosidase IC (EC 3.2.1.113) (HMIC) (Mannosidase alpha class 1C member 1) (Processing alpha-1,2-mannosidase IC) (Alpha-1,2-mannosidase IC)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000117643 )
Evolutionary StageEukaryota
AlphaFoldDBQ9NR34
Gene CardMAN1C1
Uniprot IDQ9NR34
PfamPF01532
In ASDno
Allosteric Predictionno (-1.492477607)
Ortholog in AnimalsAlpaca_ MAN1C1 ( ortholog_one2one )
Dog_ MAN1C1 ( ortholog_one2one )
GuineaPig_ MAN1C1 ( ortholog_one2one )
Macaque_ MAN1C1 ( ortholog_one2one )
Mouse_ Man1c1 ( ortholog_one2one )
Pig_ MAN1C1 ( ortholog_one2one )
Rat_ Man1c1 ( ortholog_one2one )
OhnologsMAN1A1, MAN1A2
ParalogsMAN1A2, MAN1A1, MAN1B1, EDEM1, EDEM2, EDEM3
TissueNA
Tissue SpecificityExpressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Golgi apparatus membrane;
Single-pass type II membrane protein.
Mouse PG classificationNA
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