| Gene Information | |
|---|---|
| Gene Name | HEM45 |
| Organism | Homo sapiens (Human) |
| Gene Length | 181 |
| Protein Names | Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Estrogen-regulated transcript 45 protein) (Promyelocytic leukemia nuclear body-associated protein ISG20) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96AZ6 |
| Gene Card | ISG20 |
| Uniprot ID | Q96AZ6 |
| Pfam | PF00929 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines. {ECO:0000269|PubMed:9235947, ECO:0000269|PubMed:9569007}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WLJ (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body. |
| Mouse PG classification | NA |
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