| Gene Information | |
|---|---|
| Gene Name | CST8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 142 |
| Protein Names | Cystatin-8 (Cystatin-related epididymal spermatogenic protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000125815 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O60676 |
| Gene Card | CST8 |
| Uniprot ID | O60676 |
| Pfam | PF00031 |
| In ASD | no |
| Allosteric Prediction | no (-1.599022957) |
| Ortholog in Animals | Alpaca_ CST8 ( ortholog_one2one ) Dog_ CST8 ( ortholog_one2one ) GuineaPig_ CST8 ( ortholog_one2one ) Macaque_ CST8 ( ortholog_one2one ) Mouse_ Cst8 ( ortholog_one2one ) Rat_ Cst8 ( ortholog_one2one ) Rabbit_ CST8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CST3, CST2, CST4, CST1, CST5, CST9, CST9L, CSTL1, CST11, CST6, CST7 |
| Tissue | testis |
| Tissue Specificity | Proximal caput region of the epididymis. Lower expression in the testis. Within the testis it is localized to the elongating spermatids, whereas within the epididymis it is exclusively synthesized by the proximal caput epithelium. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35190670 rs1054633 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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