| Gene Information | |
|---|---|
| Gene Name | MAGT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | Magnesium transporter protein 1 (MagT1) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1) (Oligosaccharyl transferase subunit MAGT1) (Implantation-associated protein) (IAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000102158 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9H0U3 |
| Gene Card | MAGT1 |
| Uniprot ID | Q9H0U3 |
| Pfam | PF04756 |
| In ASD | no |
| Allosteric Prediction | no (-0.550775559) |
| Ortholog in Animals | Alpaca_ MAGT1 ( ortholog_one2one ) Dog_ MAGT1 ( ortholog_one2one ) GuineaPig_ MAGT1 ( ortholog_one2one ) Macaque_ MAGT1 ( ortholog_one2one ) Mouse_ Magt1 ( ortholog_one2one ) Pig_ MAGT1 ( ortholog_one2one ) Rat_ Magt1 ( ortholog_one2one ) Rabbit_ MAGT1 ( ortholog_one2one ) |
| Ohnologs | TUSC3 |
| Paralogs | TUSC3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed at very low levels in brain, lung and kidney. {ECO:0000269|PubMed:12887896, ECO:0000269|PubMed:15804357, ECO:0000269|PubMed:19717468, ECO:0000269|PubMed:31036665}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.209582(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6S7T (EM 3.50A ) |
| DBSNP | rs145245774 rs373260156 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19717468}; Multi-pass membrane protein {ECO:0000269|PubMed:19717468}. Endoplasmic reticulum {ECO:0000269|PubMed:25135935}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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