| Gene Information | |
|---|---|
| Gene Name | MAGI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1481 |
| Protein Names | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000081026 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5TCQ9 |
| Gene Card | MAGI3 |
| Uniprot ID | Q5TCQ9 |
| Pfam | PF00625; PF00595; PF00397 |
| In ASD | no |
| Allosteric Prediction | yes (0.574442343) |
| Ortholog in Animals | Alpaca_ MAGI3 ( ortholog_one2one ) Dog_ MAGI3 ( ortholog_one2one ) GuineaPig_ MAGI3 ( ortholog_one2one ) Macaque_ MAGI3 ( ortholog_one2one ) Mouse_ Magi3 ( ortholog_one2one ) Pig_ MAGI3 ( ortholog_one2one ) Rat_ Magi3 ( ortholog_one2one ) Rabbit_ MAGI3 ( ortholog_one2one ) |
| Ohnologs | MAGI1, MAGI2 |
| Paralogs | MAGI2, SAV1, GRIP1, MAGIX, GRIP2, MAGI1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10748157}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3SOE (X-ray 1.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Nucleus {ECO:0000250}. Note=Concentrates in specific sites at the plasma membrane and in the nucleus. In epithelial cells, it localizes at tight junctions (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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