| Gene Information | |
|---|---|
| Gene Name | PYROXD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 500 |
| Protein Names | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000121350 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8WU10 |
| Gene Card | PYROXD1 |
| Uniprot ID | Q8WU10 |
| Pfam | PF07992; PF18267 |
| In ASD | no |
| Allosteric Prediction | no (-1.538404775) |
| Ortholog in Animals | Alpaca_ PYROXD1 ( ortholog_one2one ) Dog_ PYROXD1 ( ortholog_one2one ) GuineaPig_ PYROXD1 ( ortholog_one2one ) Macaque_ PYROXD1 ( ortholog_one2one ) Mouse_ Pyroxd1 ( ortholog_one2one ) Pig_ PYROXD1 ( ortholog_one2one ) Rat_ Pyroxd1 ( ortholog_one2one ) Rabbit_ PYROXD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TXNRD3, AIFM3, AIFM1, DLD, TXNRD2, TXNRD1, GSR |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ZK7 (X-ray 3.20A ) |
| DBSNP | rs781565158 rs755208949 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:27745833}. Cytoplasm {ECO:0000269|PubMed:27745833}. Cytoplasm, myofibril, sarcomere {ECO:0000269|PubMed:27745833}. |
| Mouse PG classification | NA |
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