| Gene Information | |
|---|---|
| Gene Name | MAGEA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | Melanoma-associated antigen 2 (Cancer/testis antigen 1.2) (CT1.2) (MAGE-2 antigen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000268606 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P43356 |
| Gene Card | MAGEA2;MAGEA2B |
| Uniprot ID | P43356 |
| Pfam | PF01454; PF12440 |
| In ASD | no |
| Allosteric Prediction | no (-0.76354331) |
| Ortholog in Animals | Mouse_ Magea13 ( ortholog_many2many ) Rat_ Magea13 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | MAGED4, MAGED4B, MAGEB17, MAGEB1, MAGEA3, MAGEA6, MAGEL2, NDN, MAGEB6, MAGEB6B, MAGEB2, MAGEH1, MAGEA8, MAGEE2, MAGEA11, MAGEB5, MAGED1, MAGEB10, MAGEA10, MAGEA4, TRO, MAGEB4, MAGEC3, MAGEE1, MAGEA9, MAGEA9B, MAGEB3, MAGEC1, MAGEC2, NSMCE3, MAGEA1, MAGEB18, MAGEB16, MAGEF1, MAGED2, MAGEA2B, MAGEA12 |
| Tissue | NA |
| Tissue Specificity | Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Nucleus, PML body. |
| Mouse PG classification | NA |
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