| Gene Information | |
|---|---|
| Gene Name | EPS8L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 723 |
| Protein Names | Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8-like protein 1) (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-related protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000131037 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TE68 |
| Gene Card | EPS8L1 |
| Uniprot ID | Q8TE68 |
| Pfam | PF08416; PF18016; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-1.127917762) |
| Ortholog in Animals | Alpaca_ EPS8L1 ( ortholog_one2one ) Dog_ EPS8L1 ( ortholog_one2one ) Macaque_ EPS8L1 ( ortholog_one2many ) Mouse_ Eps8l1 ( ortholog_one2one ) Pig_ EPS8L1 ( ortholog_one2one ) Rat_ Eps8l1 ( ortholog_one2one ) |
| Ohnologs | EPS8L2 |
| Paralogs | EPS8L2, EPS8L3, EPS8 |
| Tissue | esophagus.mucosa, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Detected in placenta. {ECO:0000269|PubMed:14565974}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2K2M (NMR - ) 2ROL (NMR - ) |
| DBSNP | rs12609976 rs1620074 rs1628576 rs1054940 rs60073068 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14565974}. |
| Mouse PG classification | NA |
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