Gene Information
Gene NameMADH5
OrganismHomo sapiens (Human)
Gene Length465
Protein NamesMothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (JV5-1) (SMAD family member 5) (SMAD 5) (Smad5) (hSmad5)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ99717
Gene CardSMAD5
Uniprot IDQ99717
PfamPF03165; PF03166
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous.
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);0.001823(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6FZS  (X-ray  2.31A  6TCE  (X-ray  2.92A 
DBSNP NA 
Subcellular location [CC]Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
Mouse PG classificationNA
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