| Gene Information | |
|---|---|
| Gene Name | ADORA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 326 |
| Protein Names | Adenosine receptor A1 |
| Target Name | adora1 messenger rna |
| Target Type | Clinical trial target |
| Gene Age | 950 ( ENSG00000163485 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P30542 |
| Gene Card | ADORA1 |
| Uniprot ID | P30542 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.716535802) |
| Ortholog in Animals | Alpaca_ ADORA1 ( ortholog_one2one ) Dog_ ADORA1 ( ortholog_one2one ) GuineaPig_ ADORA1 ( ortholog_one2one ) Macaque_ ADORA1 ( ortholog_one2one ) Mouse_ Adora1 ( ortholog_one2one ) Pig_ ADORA1 ( ortholog_one2one ) Rat_ Adora1 ( ortholog_one2one ) Rabbit_ ADORA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ADORA3, ADORA2A, ADORA2B |
| Tissue | cerebral.cortex, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004990(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5N2S (X-ray 3.30A ) 5UEN (X-ray 3.20A ) 6D9H (EM 3.60A ) 7LD3 (EM 3.20A ) 7LD4 (EM 3.30A ) |
| DBSNP | rs11547175 rs11547174 rs11547176 rs899207013 rs17852405 rs748346254 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:27134041}; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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