Gene Information
Gene NameMACO1
OrganismHomo sapiens (Human)
Gene Length664
Protein NamesMacoilin (Macoilin-1) (Transmembrane protein 57)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000204178 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8N5G2
Gene CardMACO1
Uniprot IDQ8N5G2
PfamPF09726
In ASDno
Allosteric Predictionno (-1.075275464)
Ortholog in AnimalsAlpaca_ MACO1 ( ortholog_one2one )
Dog_ MACO1 ( ortholog_one2one )
GuineaPig_ MACO1 ( ortholog_one2one )
Macaque_ MACO1 ( ortholog_one2one )
Mouse_ Maco1 ( ortholog_one2one )
Pig_ MACO1 ( ortholog_one2one )
Rat_ Maco1 ( ortholog_one2one )
Rabbit_ MACO1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus membrane {ECO:0000250|UniProtKB:Q7TQE6};
Multi-pass membrane protein {ECO:0000255}. Cell projection, axon {ECO:0000250|UniProtKB:Q7TQE6}. Rough endoplasmic reticulum membrane {ECO:0000269|PubMed:21589894};
Multi-pass membrane protein {ECO:0000255}. Note=Detected in the nucleus membrane of non-neuronal cells and in axonal outgrowths of neuronal cells. {ECO:0000250|UniProtKB:Q7TQE6}.
Mouse PG classificationNA
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