| Gene Information | |
|---|---|
| Gene Name | STAM |
| Organism | Homo sapiens (Human) |
| Gene Length | 540 |
| Protein Names | Signal transducing adapter molecule 1 (STAM-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000136738 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92783 |
| Gene Card | STAM |
| Uniprot ID | Q92783 |
| Pfam | PF00018; PF02809; PF00790 |
| In ASD | no |
| Allosteric Prediction | yes (0.455504017) |
| Ortholog in Animals | Alpaca_ STAM ( ortholog_one2one ) Dog_ STAM ( ortholog_one2one ) GuineaPig_ STAM ( ortholog_one2one ) Macaque_ STAM ( ortholog_one2one ) Mouse_ Stam ( ortholog_one2one ) Pig_ STAM ( ortholog_one2one ) Rat_ Stam ( ortholog_one2one ) Rabbit_ STAM ( ortholog_one2one ) |
| Ohnologs | STAM2 |
| Paralogs | WDFY2, STAM2, HGS, GGA1, TOM1, WDFY1, TOM1L2, GGA3, GGA2, TOM1L1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:8780729}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.080972(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2L0A (NMR - ) 3F1I (X-ray 2.30A ) 3LDZ (X-ray 2.60A ) |
| DBSNP | rs1554827317 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. Early endosome membrane {ECO:0000269|PubMed:23166352, ECO:0000269|PubMed:24790097}; Peripheral membrane protein {ECO:0000305|PubMed:23166352, ECO:0000305|PubMed:24790097}; Cytoplasmic side {ECO:0000305|PubMed:23166352, ECO:0000305|PubMed:24790097}. |
| Mouse PG classification | NA |
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